The antioxidant protein peroxiredoxin 4 is epigenetically down regulated in acute promyelocytic leukemia.

The antioxidant peroxiredoxin (PRDX) protein family comprises 6 members, which are implicated in a variety of cellular responses, including growth factor signal transduction. PRDX4 resides in the endoplasmic reticulum (ER), where it locally controls oxidative stress by reducing H(2)O(2) levels. We r...

詳細記述

書誌詳細
出版年:PLoS ONE
主要な著者: Karishma K Palande, Renee Beekman, Lotte E van der Meeren, H Berna Beverloo, Peter J M Valk, Ivo P Touw
フォーマット: 論文
言語:英語
出版事項: Public Library of Science (PLoS) 2011-01-01
オンライン・アクセス:http://europepmc.org/articles/PMC3024432?pdf=render