Human Bone Marrow Stromal Cells Lose Immunosuppressive and Anti-inflammatory Properties upon Oncogenic Transformation

Because of their immunomodulatory properties, human bone marrow stromal cells (hBMSCs) represent promising stem cells for treatment of immune disorders. hBMSCs expansion precedes their clinical use, so the possibility that hBMSCs undergo spontaneous transformation upon long-term culture should be ad...

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Bibliographic Details

Published in:	Stem Cell Reports
Main Authors:	Rene Rodriguez, Michael Rosu-Myles, Marcos Aráuzo-Bravo, Angélica Horrillo, Qiuwei Pan, Elena Gonzalez-Rey, Mario Delgado, Pablo Menendez
Format:	Article
Language:	English
Published:	Elsevier 2014-10-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213671114002598