Development and characterization of an intraocular biodegradable polymer system containing cyclosporine-A for the treatment of posterior uveitis

The aim of this study was to synthesize and characterize the biodegradable intraocular implants based on poly (D,L-lactide-co-glycolide) (PLGA 75:25) with Cyclosporine-A (CyA) and to evaluate their in vitro drug delivery profile. Thermal analysis was conducted by using Thermogravimetry (TG) and Diff...

Full description

Bibliographic Details

Published in:	Materials Research
Main Authors:	Juliana Barbosa Saliba, André Augusto Gomes Faraco, Maria Irene Yoshida, Wander Luiz de Vasconcelos, Armando da Silva-Cunha, Herman Sander Mansur
Format:	Article
Language:	English
Published:	Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol) 2008-06-01
Subjects:	nanostructured drug delivery system biodegradable intraocular implants biodegradable polymer
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392008000200016