Fusogenic lipid nanoparticles for rapid delivery of large therapeutic molecules to exosomes

Abstract Exosomes, as cell-derived lipid nanoparticles, are promising drug carriers because they can traverse challenging physiological barriers such as the blood-brain barrier (BBB). However, a major obstacle in utilizing exosomes as drug carriers is loading large therapeutic molecules without comp...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Gamsong Son, Jiyoung Song, Jae Chul Park, Hong Nam Kim, Hojun Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Online Access:https://doi.org/10.1038/s41467-025-59489-5