Structural and functional characterization of cyclic pyrimidine-regulated anti-phage system

Abstract 3’,5’-cyclic uridine monophosphate (cUMP) and 3’,5’-cyclic cytidine monophosphate (cCMP) have been established as bacterial second messengers in the phage defense system, named pyrimidine cyclase system for anti-phage resistance (Pycsar). This system consists of a pyrimidine cyclase and a c...

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發表在:Nature Communications
Main Authors: Mei-Hui Hou, Chao-Jung Chen, Chia-Shin Yang, Yu-Chuan Wang, Yeh Chen
格式: Article
語言:英语
出版: Nature Portfolio 2024-07-01
在線閱讀:https://doi.org/10.1038/s41467-024-49861-2