Cryo-EM structure of single-layered nucleoprotein-RNA complex from Marburg virus

Abstract Marburg virus (MARV) causes lethal hemorrhagic fever in humans, posing a threat to global health. We determined by cryogenic electron microscopy (cryo-EM) the MARV helical ribonucleoprotein (RNP) complex structure in single-layered conformation, which differs from the previously reported st...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Luca Zinzula, Florian Beck, Marianna Camasta, Stefan Bohn, Chuan Liu, Dustin Morado, Andreas Bracher, Juergen M. Plitzko, Wolfgang Baumeister
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Online Access:https://doi.org/10.1038/s41467-024-54431-7