Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues.

The DNA binding domain of Transcription Activator-Like (TAL) effectors can easily be engineered to have new DNA sequence specificities. Consequently, engineered TAL effector proteins have become important reagents for manipulating genomes in vivo. DNA binding by TAL effectors is mediated by arrays o...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Michelle L Christian, Zachary L Demorest, Colby G Starker, Mark J Osborn, Michael D Nyquist, Yong Zhang, Daniel F Carlson, Philip Bradley, Adam J Bogdanove, Daniel F Voytas
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	http://europepmc.org/articles/PMC3454392?pdf=render