Structural basis for the evolution and antibody evasion of SARS-CoV-2 BA.2.86 and JN.1 subvariants

Abstract The Omicron subvariants of SARS-CoV-2, especially for BA.2.86 and JN.1, have rapidly spread across multiple countries, posing a significant threat in the ongoing COVID-19 pandemic. Distinguished by 34 additional mutations on the Spike (S) protein compared to its BA.2 predecessor, the implic...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Haonan Yang, Huimin Guo, Aojie Wang, Liwei Cao, Qing Fan, Jie Jiang, Miao Wang, Lin Lin, Xiangyang Ge, Haiyan Wang, Runze Zhang, Ming Liao, Renhong Yan, Bin Ju, Zheng Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Online Access:https://doi.org/10.1038/s41467-024-51973-8