Syphilis and the host: multi-omic analysis of host cellular responses to Treponema pallidum provides novel insight into syphilis pathogenesis

IntroductionSyphilis is a chronic, multi-stage infection caused by the extracellular bacterium Treponema pallidum ssp. pallidum. Treponema pallidum widely disseminates through the vasculature, crosses endothelial, blood–brain and placental barriers, and establishes systemic infection. Although the c...

Full description

Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Sean Waugh, Akash Ranasinghe, Alloysius Gomez, Simon Houston, Karen V. Lithgow, Azad Eshghi, Jenna Fleetwood, Kate M. E. Conway, Lisa A. Reynolds, Caroline E. Cameron
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-09-01
Subjects:	syphilis Treponema pallidum proteomics dissemination disease symptoms
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1254342/full