Off-Target Effect of Activation of NF-κB by HIV Latency Reversal Agents on Transposable Elements Expression

Many drugs have been evaluated to reactivate HIV-1 from cellular reservoirs, but the off-target effects of these latency reversal agents (LRA) remain poorly defined. Transposable elements (TEs) are reactivated during HIV-1 infection, but studies of potential off-target drug effects on TE expression...

Full description

Bibliographic Details

Published in:	Viruses
Main Authors:	Gislaine Curty, Luis P. Iniguez, Marcelo A. Soares, Douglas F. Nixon, Miguel de Mulder Rougvie
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Subjects:	transposable elements human endogenous retroviruses HERV LINE-1 HIV-1 latency reversal agents
Online Access:	https://www.mdpi.com/1999-4915/14/7/1571