Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs, and mRNAs in live bacterial cells

RNA-binding proteins play myriad roles in regulating RNAs and RNA-mediated functions. In bacteria, the RNA chaperone Hfq is an important post-transcriptional gene regulator. Using live-cell super-resolution imaging, we can distinguish Hfq binding to different sizes of cellular RNAs. We demonstrate t...

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Bibliographic Details

Published in:	eLife
Main Authors:	Seongjin Park, Karine Prévost, Emily M Heideman, Marie-Claude Carrier, Muhammad S Azam, Matthew A Reyer, Wei Liu, Eric Massé, Jingyi Fei
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2021-02-01
Subjects:	hfq sRNA gene regulation single-particle tracking super-resolution imaging
Online Access:	https://elifesciences.org/articles/64207