Binding Orientations and Lipid Interactions of Human Amylin at Zwitterionic and Anionic Lipid Bilayers
Increasing evidence suggests that the interaction of human islet amyloid polypeptide (hIAPP) with lipids may facilitate hIAPP aggregation and cause the death of pancreatic islet β-cells. However, the detailed hIAPP-membrane interactions and the influences of lipid compositions are unclear. In this s...
| Published in: | Journal of Diabetes Research |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
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| Online Access: | http://dx.doi.org/10.1155/2016/1749196 |