MyD88 is a critical regulator of hematopoietic cell-mediated neuroprotection seen after stroke.

Neuroinflammation is critical in the neural cell death seen in stroke. It has been shown that CNS and peripheral responses drive this neuroinflammatory response in the brain. The Toll-like receptors (TLRs) are important regulators of inflammation in response to both exogenous and endogenous stressor...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Catherine E Downes, Connie H Y Wong, Katya J Henley, Pedro L Guio-Aguilar, Moses Zhang, Robert Ates, Ashley Mansell, Benjamin T Kile, Peter J Crack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23483951/?tool=EBI