Screening of the antileishmanial and antiplasmodial potential of synthetic 2-arylquinoline analogs

Abstract In this study, six analogs of 2-arylquinoline were synthesized and evaluated for their in vitro and in vivo antiplasmodial and leishmanicidal activity. At a later stage, hemolytic activity and druggability were tested in vitro and in silico, respectively, observing as a result: firstly, com...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Roger Espinosa-Saez, Sara M. Robledo, Tatiana Pineda, Javier Murillo, César Zúñiga, Osvaldo Yañez, Plinio Cantero-López, Alex Saez-Vega, Camilo Guzmán-Teran
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-10-01
Online Access:	https://doi.org/10.1038/s41598-023-43805-4