Down-Regulated FOXO1 in Refractory/Relapse Childhood B-Cell Acute Lymphoblastic Leukemia

Background: Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall prevalence of 4/100,000, accounting for 25–30% of all childhood cancers. With advances in childhood ALL treatment, the cure rate for childhood ALL has exceeded 80% in most countries. However, refracto...

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Bibliographic Details
Published in:Frontiers in Oncology
Main Authors: Qingqing Zheng, Chuang Jiang, Haiyan Liu, Wenge Hao, Pengfei Wang, Haiying Huang, Ziping Li, Jiabi Qian, Maoxiang Qian, Hui Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.579673/full