Circ_PIP5K1A regulates cisplatin resistance and malignant progression in non-small cell lung cancer cells and xenograft murine model via depending on miR-493-5p/ROCK1 axis

Abstract Background Chemoresistance limits the therapeutic effect of cisplatin (DDP) on non-small cell lung cancer (NSCLC). Circular RNAs (circRNAs) function as important regulators in chemoresistance. This study aimed to explore the regulation of circRNA Phosphatidylinositol-4-Phosphate 5-Kinase Ty...

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Bibliographic Details
Published in:Respiratory Research
Main Authors: Nan Feng, Zhi Guo, Xiaokang Wu, Ying Tian, Yue Li, Yan Geng, Yan Yu
Format: Article
Language:English
Published: BMC 2021-09-01
Subjects:
Circ_PIP5K1A
miR-493-5p
ROCK1
Cisplatin resistance
Non-small cell lung cancer
Online Access:https://doi.org/10.1186/s12931-021-01840-7

Internet

https://doi.org/10.1186/s12931-021-01840-7

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