Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin

Summary: Glucose transporters are gatekeepers of cellular glucose metabolism. Understanding how their activity is regulated can provide insight into mechanisms of glucose homeostasis and diseases arising from dysregulation of glucose transport. Glucose stimulates endocytosis of the human glucose tra...

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Bibliographic Details

Published in:	iScience
Main Authors:	Susan J. Qualls-Histed, Casey P. Nielsen, Jason A. MacGurn
Format:	Article
Language:	English
Published:	Elsevier 2023-03-01
Subjects:	Biological sciences Molecular biology Cell biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223002274