Rhoptry and Dense Granule Secreted Effectors Regulate CD8+ T Cell Recognition of Toxoplasma gondii Infected Host Cells

Toxoplasma gondii secretes rhoptry (ROP) and dense granule (GRA) effector proteins to evade host immune clearance mediated by interferon gamma (IFN-γ), immunity-related GTPase (IRG) effectors, and CD8+ T cells. Here, we investigated the role of parasite-secreted effectors in regulating host access t...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Leah M. Rommereim, Barbara A. Fox, Kiah L. Butler, Viviana Cantillana, Gregory A. Taylor, David J. Bzik
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-09-01
Subjects:	Toxoplasma gondii dense granule rhoptry antigen presentation immunity related GTPases
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02104/full