Autophagy induction by SIRT6 is involved in oxidative stress-induced neuronal damage

Abstract SIRT6 is a NAD+-dependent histone deacetylase and has been implicated in the regulation of genomic stability, DNA repair, metabolic homeostasis and several diseases. The effect of SIRT6 in cerebral ischemia and oxygen/glucose deprivation (OGD) has been reported, however the role of SIRT6 in...

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Bibliographic Details
Published in:Protein & Cell
Main Authors: Jiaxiang Shao, Xiao Yang, Tengyuan Liu, Tingting Zhang, Qian Reuben Xie, Weiliang Xia
Format: Article
Language:English
Published: Oxford University Press 2016-03-01
Subjects:
SIRT6
oxidative stress
neuronal damage
autophagy
AKT
Online Access:http://link.springer.com/article/10.1007/s13238-016-0257-6

Internet

http://link.springer.com/article/10.1007/s13238-016-0257-6

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