Analysis of tricarboxylic acid cycle intermediates in dried blood spots by ultraperformance liquid chromatography-tandem mass spectrometry

Background: We developed a novel method for measuring the concentrations of tricarboxylic acid (TCA) cycle intermediates in dried blood spots (DBS) using liquid chromatography-tandem mass spectrometry (LC-MS/ MS). Analytes were derivatized before analysis using 4-[2-(N,N-dimethylamino) ethylaminosul...

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Bibliographic Details

Published in:	Journal of Biochemical and Clinical Genetics
Main Authors:	Lamia Alhammadi, Maitha Aal Abdulla, Naila Ahli, Nahid Al Dhahouri, Anas Al Aidaros, Fatma Al-Jasmi, Osama Y. Al-Dirbashi
Format:	Article
Language:	English
Published:	Discover STM Publishing Ltd 2019-12-01
Subjects:	tricarboxylic acid cycle citric acid 2-ketoglutaric acid succinic acid fumaric acid malic acid dbs lc-ms/ms daabd-ae
Online Access:	http://www.ejmanager.com/fulltextpdf.php?mno=57331