Ciprofloxacin disrupts testosterone synthesis in mice via downregulating StAR expression through NR4A1 pathway

Ciprofloxacin (CIP) is a synthetic third-generation quinolone antimicrobial agent with broad-spectrum bactericidal activity and widely used in human and veterinary medicine. Some studies have shown that quinolone antibiotics are endocrine disruptors, but the effect of early-life exposure to CIP on t...

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Bibliographic Details

Published in:	Ecotoxicology and Environmental Safety
Main Authors:	Lirui Hou, Yuhan Fu, Yue Zhao, Chongshan Dai, Chong Zhao, Lihong Fan, Hongbo Hu, Shutao Yin
Format:	Article
Language:	English
Published:	Elsevier 2025-09-01
Subjects:	Ciprofloxacin Testosterone StAR NR4A1
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651325008565