Single-Cell Transcriptomics Reveals Endothelial Plasticity During Diabetic Atherogenesis

Atherosclerosis is the leading cause of cardiovascular diseases, which is also the primary cause of mortality among diabetic patients. Endothelial cell (EC) dysfunction is a critical early step in the development of atherosclerosis and aggravated in the presence of concurrent diabetes. Although the...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Guizhen Zhao, Haocheng Lu, Yuhao Liu, Yang Zhao, Tianqing Zhu, Minerva T. Garcia-Barrio, Y. Eugene Chen, Jifeng Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-05-01
Subjects:	single-cell RNA-sequencing endothelial cell transcriptomic heterogeneity diabetes atherosclerosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.689469/full