Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New Guinea

Abstract Background Children in third-world settings including Papua New Guinea (PNG) experience early onset of carriage with a broad range of pneumococcal serotypes, resulting in a high incidence of severe pneumococcal disease and deaths in the first 2 years of life. Vaccination trials in high ende...

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Bibliographic Details

Published in:	Pneumonia
Main Authors:	Deborah Lehmann, Wendy Kirarock, Anita H. J. van den Biggelaar, Megan Passey, Peter Jacoby, Gerard Saleu, Geraldine Masiria, Birunu Nivio, Andrew Greenhill, Tilda Orami, Jacinta Francis, Rebecca Ford, Lea-Ann Kirkham, Vela Solomon, Peter C. Richmond, William S. Pomat, for the 10v13v PCV trial team
Format:	Article
Language:	English
Published:	BMC 2017-12-01
Subjects:	Pneumococcal Vaccine PCV PPV Pneumococcal conjugate vaccine Pneumococcal polysaccharide vaccine
Online Access:	http://link.springer.com/article/10.1186/s41479-017-0044-z