Hapten-labeled DNA probes can be stored and used in fluorescence in situ hybridization for decades

In molecular cytogenetics, fluorescence in situ hybridization (FISH) is the main technique used. In both research and diagnostics, FISH depends on well-defined and mapped DNA probes that produce brilliant signals with minimal background, visible in metaphases and/or interphases. Such probes are eith...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Thomas Liehr, Niklas Padutsch, Stefanie Kankel
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	fluorescence in situ hybridization molecular cytogenetics indirect labeling direct labeling commercial probes homemade probes
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2025.1569308/full