Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathway

Abstract Accumulating evidence implicates that herpes simplex virus type 1 (HSV-1) has been linked to the development and progression of Alzheimer’s disease (AD). HSV-1 infection induces β-amyloid (Aβ) deposition in vitro and in vivo, but the effect and precise mechanism remain elusive. Here, we sho...

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Bibliographic Details

Published in:	Journal of Neuroinflammation
Main Authors:	Zhimeng Wang, Jing Liu, Jing Han, Tianyi Zhang, Shangjin Li, Yanfei Hou, Huili Su, Fangping Han, Conggang Zhang
Format:	Article
Language:	English
Published:	BMC 2024-07-01
Online Access:	https://doi.org/10.1186/s12974-024-03166-9