Loss of Adenosine Deaminase Acting on RNA 1 Induces Panoptosis and Immune Response in Ulcerative Colitis Gut Mucosa

ABSTRACT The gut virome is a complex community that exists in equilibrium with the host. Disruptions of this balance could drive the development of inflammatory diseases, such as inflammatory bowel disease (IBD). RNA editing, particularly A‐to‐I editing by ADAR1, prevents the excessive immune respon...

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Bibliographic Details

Published in:	MedComm
Main Authors:	Andrea Iannucci, Marco Colella, Macarena Quiroga, Rachele Frascatani, Lorenzo Tomassini, Claudia Maresca, Eleonora Franzè, Federica Laudisi, Giuseppe Sica, Irene Marafini, Alessandro Michienzi, Ivan Zanoni, Giovanni Monteleone, Ivan Monteleone
Format:	Article
Language:	English
Published:	Wiley 2025-06-01
Subjects:	adenosine deaminase acting on RNA 1 inflammatory bowel disease innate immunity mucosal damage panoptosis
Online Access:	https://doi.org/10.1002/mco2.70212