2-((1H-Benzo[d]imidazol-2-yl)amino)benzo[d]thiazole-6-sulphonamides: a class of carbonic anhydrase II and VII-selective inhibitors

A small library of substituted cyclic guanidine incorporated benzothiazole-6-sulphonamides was synthesized. All obtained compounds were investigated for their inhibitory activity against the key brain-associated human carbonic anhydrase isoform hCA VII (a promising target for the treatment of neurop...

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Bibliographic Details

Published in:	Journal of Enzyme Inhibition and Medicinal Chemistry
Main Authors:	Morteza Abdoli, Claudiu T. Supuran, Raivis Žalubovskis
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Subjects:	Carbonic anhydrase isozyme VII neuropathic pain sulphonamides guanidines inhibitors
Online Access:	https://www.tandfonline.com/doi/10.1080/14756366.2023.2174981