Higher serum sPD-L1 levels after radiotherapy indicate poor outcome in hepatocellular carcinoma patients

Background: Our preclinical research reveals that radiotherapy (RT) promoted PD-L1 upregulation in tumor tissues and that higher PD-L1 after RT worsened the prognosis through immunosuppression. We sought to validate our experimental results in clinical cohorts and promote clinical application. Patie...

Full description

Bibliographic Details

Published in:	Translational Oncology
Main Authors:	Yang Zhang, Zongjuan Li, Yixing Chen, Ping Yang, Yong Hu, Zhaochong Zeng, Shisuo Du
Format:	Article
Language:	English
Published:	Elsevier 2022-12-01
Subjects:	Hepatocellular carcinoma Soluble PD-L1 Immune regulation Radiother apy Prognosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523322001966