OnmiMHC: a machine learning solution for UCEC tumor vaccine development through enhanced peptide-MHC binding prediction

The key roles of Major Histocompatibility Complex (MHC) Class I and II molecules in the immune system are well established. This study aims to develop a novel machine learning framework for predicting antigen peptide presentation by MHC Class I and II molecules. By integrating large-scale mass spect...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Fangfang Jian, Haihua Cai, Qushuo Chen, Xiaoyong Pan, Weiwei Feng, Ye Yuan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Subjects:	peptide-MHC binding MHC I and II deep learning uterine corpus endometrial carcinoma neoantigen
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1550252/full