Glycosaminoglycan sugar side chains on perineuronal nets in the fastigial nucleus regulate motor skills

Summary: Perineuronal nets (PNNs), composed primarily of chondroitin sulfate proteoglycans with core proteins and glycosaminoglycan (GAG) side chains, are specialized extracellular matrices that modulate synaptic transmission. However, the specific function of PNNs in the cerebellum, particularly in...

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Bibliographic Details

Published in:	iScience
Main Authors:	Man Han, Peng Fu, Chuan-lin Zhang, Jing-wen Duan, Tong Wu, Yan Zeng
Format:	Article
Language:	English
Published:	Elsevier 2025-08-01
Subjects:	Natural sciences Biological sciences Neuroscience Systems neuroscience Neuroanatomy Behavioral neuroscience
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004225012131