Identification of key modules and hub genes for sepsis-induced myopathy using weighted gene co-expression network analysis

BackgroundSepsis-induced myopathy (SIM) is a severe complication of sepsis, leading to significant muscle dysfunction and increased mortality. The molecular mechanisms underlying SIM remain poorly understood, necessitating comprehensive studies to identify potential therapeutic targets. This study a...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Siming Lin, Kexin Cai, Ai Chen, Weibin Wu, Guili Lian, Shaodan Feng, Zhihong Lin, Liangdi Xie
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	sepsis-induced myopathy skeletal muscle hub genes biomarkers bioinformatics WGCNA
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2025.1607575/full