ALKBH5 in development: decoding the multifaceted roles of m6A demethylation in biological processes

N6-methyladenosine (m6A), an abundant internal RNA modification in eukaryotes, serves as a dynamic post-transcriptional regulator of gene expression by influencing RNA splicing, stability, translation, and decay. This reversible epitranscriptomic mechanism, which is mediated by methyltransferase (wr...

Full description

Bibliographic Details

Published in:	Frontiers in Molecular Biosciences
Main Authors:	Xinye Zhang, Linfang Zhou, Cheng Tian, Huangheng Tao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	ALKBH5 m6A demethylation development organogenesis therapeutics
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2025.1599487/full