G-Quadruplex-Binding Proteins: Promising Targets for Drug Design

G-quadruplexes (G4s) are non-canonical secondary nucleic acid structures. Sequences with the potential to form G4s are abundant in regulatory regions of the genome including telomeres, promoters and 5′ non-coding regions, indicating they fulfill important genome regulatory functions. Generally, G4s...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Huiling Shu, Rongxin Zhang, Ke Xiao, Jing Yang, Xiao Sun
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Subjects:	G-quadruplex G-quadruplex-binding protein drug target G4 diseases therapeutics
Online Access:	https://www.mdpi.com/2218-273X/12/5/648