Polymeric nanoparticles containing kojic acid induce structural alterations and apoptosis-like death in Leishmania (Leishmania) amazonensis

Leishmaniasis encompasses a cluster of neglected tropical diseases triggered by kinetoplastid phatogens belonging to the genus Leishmania. Current therapeutic approaches are toxic, expensive, and require long-term treatment. Nanoparticles are emerging as a new alternative for the treatment of neglec...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Poliana Queiroz-Souza, Adan Galue-Parra, Lienne Silveira Moraes, Caroline Gomes Macedo, Ana Paula Drummond Rodrigues, Victor H. S. Marinho, Fabricio H. Holanda, Irlon M. Ferreira, Edilene Oliveira da Silva
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	leishmanicidal activity nanoparticle kojic acid silk fibroin drug delivery system
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1331240/full