Site-specific, insertional inactivation of incA in Chlamydia trachomatis using a group II intron.

Chlamydia trachomatis is an obligate, intracellular bacterial pathogen that has until more recently remained recalcitrant to genetic manipulation. However, the field still remains hindered by the absence of tools to create selectable, targeted chromosomal mutations. Previous work with mobile group I...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Cayla M Johnson, Derek J Fisher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Online Access:http://europepmc.org/articles/PMC3877132?pdf=render