TNFα Signaling Is Increased in Progressing Oral Potentially Malignant Disorders and Regulates Malignant Transformation in an Oral Carcinogenesis Model

Oral carcinogenesis represents a multi-stage process which encompasses several genetic and molecular changes that promote the progression of oral potentially malignant disorders (OPMDs) to oral squamous cell carcinomas (OSCCs). A better understanding of critical pathways governing the progression of...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Jeffrey W. Chadwick, Rachel Macdonald, Aiman A. Ali, Michael Glogauer, Marco A. Magalhaes
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-09-01
Subjects:	carcinogenesis squamous cell carcinoma dysplasia neutrophils inflammation TNFa
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2021.741013/full