Conjugated Bilirubin Differentially Regulates CD4+ T Effector Cells and T Regulatory Cell Function through Outside-In and Inside-Out Mechanisms: The Effects of HAV Cell Surface Receptor and Intracellular Signaling

We recently reported an immune-modulatory role of conjugated bilirubin (CB) in hepatitis A virus (HAV) infection. During this infection the immune response relies on CD4+ T lymphocytes (TLs) and it may be affected by the interaction of HAV with its cellular receptor (HAVCR1/TIM-1) on T cell surface....

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Bibliographic Details

Published in:	Mediators of Inflammation
Main Authors:	Karla F. Corral-Jara, Jorge L. Trujillo-Ochoa, Mauricio Realpe, Arturo Panduro, Juan F. Gómez-Leyva, Yvonne Rosenstein, Alexis Jose-Abrego, Sonia Roman, Nora A. Fierro
Format:	Article
Language:	English
Published:	Wiley 2016-01-01
Online Access:	http://dx.doi.org/10.1155/2016/1759027