The role of in vitro testing in pharmacovigilance for ß-lactam-induced serum sickness-like reaction: A pilot study

Background: Current pharmacovigilance (PV) methods for detection of adverse drug reactions (ADRs) fail to capture rare immune-mediated drug hypersensitivity reactions (DHRs) due to their scarcity and the lack of clear diagnostic criteria. Drug-induced serum sickness-like reactions (SSLRs) are rare t...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Abdelbaset A. Elzagallaai, Awatif M. Abuzgaia, Blanca R. Del Pozzo-Magaña, Eman Loubani, Michael J. Rieder
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Subjects:	drug hypersensitivity pharmacovigilance beta-lactam agents serum sickness-like reaction adverse drug reaction
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.945545/full