Resolving the Haplotype Complexity of Colorectal Cancer Genomes with Droplet Barcode Sequencing

Precision medicine is increasingly applied in the cancer clinic, adapting treatment to genomic alterations of the tumor. However, whether alterations disrupt the function of a protein can depend on if both alleles of a gene are altered. While massively parallel sequencing technologies can identify s...

Full description

Bibliographic Details
Published in:Life
Main Authors: Humam Siga, Pontus Höjer, Parham Pourbozorgi, Hooman Aghelpasand, Max Käller, Johan Hartman, Cecilia Williams, Afshin Ahmadian
Format: Article
Language:English
Published: MDPI AG 2026-05-01
Subjects:
cancer genomics
colorectal cancer
CRC
linked-reads
haplotyping
droplet barcode sequencing
Online Access:https://www.mdpi.com/2075-1729/16/6/874

Internet

https://www.mdpi.com/2075-1729/16/6/874

Similar Items