End-point determination of heterogeneous formulations using inline torque measurements for a high-shear wet granulation process

In this study, the torque profiles of heterogeneous granulation formulations with varying powder properties in terms of particle size, solubility, deformability, and wettability, were studied, and the feasibility of identifying the end-point of the granulation process for each formulation based on t...

詳細記述

書誌詳細

出版年:	International Journal of Pharmaceutics: X
主要な著者:	Ashley Dan, Haresh Vaswani, Alice Šimonová, Aleksandra Grząbka-Zasadzińska, Jingzhe Li, Koyel Sen, Shubhajit Paul, Yin-Chao Tseng, Rohit Ramachandran
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-12-01
主題:	Wet granulation Torque End-point determination Growth regimes Over-granulation Porosity
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2590156723000324