Radiation Necrosis Following Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy with High Biologically Effective Doses for Large Brain Metastases

In Radiation Therapy Oncology Group 90-05, the maximum tolerated dose of single-fraction radiosurgery (SRS) for brain metastases of 21–30 mm was 18 Gy (biologically effective dose (BED) 45 Gy₁₂). Since the patients in this study received prior brain irradiation, tolerable BED...

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Bibliographic Details

Published in:	Biology
Main Authors:	Leonie Johannwerner, Elisa M. Werner, Oliver Blanck, Stefan Janssen, Florian Cremers, Nathan Y. Yu, Dirk Rades
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Subjects:	brain metastasis radiation necrosis stereotactic radiosurgery fractionated stereotactic radiotherapy biologically effective dose
Online Access:	https://www.mdpi.com/2079-7737/12/5/655