Neuroprotective role of morin hydrate on 3-nitropropionic acid-elicited huntington's disease: in vivo investigation of RIPK1/RIPK3/MLKL necroptosis signaling pathway

Abstract Background Huntington’s disease (HD) is a rare dominantly inheritable autosomal neurodegenerative disease with unclear pathophysiological pathways. In neurodegenerative disorders, including HD, necroptosis plays a significant role in neuronal death. Morin hydrate (MH), a natural bioactive f...

全面介紹

書目詳細資料

發表在:	Molecular Medicine
Main Authors:	Eman M. Elbaz, Rabab H. Sayed, Amany A. Abdelkader, Atef Tadros Fahim
格式:	Article
語言:	英语
出版:	BMC 2025-04-01
主題:	Huntington’s disease Morin hydrate Necroptosis Necrosulfonamide 3-nitropropionic acid
在線閱讀:	https://doi.org/10.1186/s10020-025-01172-y