Towards a quality control framework for cerebral cortical organoids

Abstract Cerebral organoids offer significant potential for neuroscience research as complex in vitro models that mimic human brain development. However, challenges related to their quality and reproducibility hinder their reliability. Discrepancies in morphology, size, cellular composition, and cyt...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Héloïse Castiglione, Lucie Madrange, Camille Baquerre, Benoît Guy Christian Maisonneuve, Thomas Lemonnier, Jean-Philippe Deslys, Frank Yates, Thibault Honegger, Jessica Rontard, Pierre-Antoine Vigneron
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-08-01
Subjects:	Cerebral organoids Quality control Hierarchical scoring methodology Reproducibility Standardization.
Online Access:	https://doi.org/10.1038/s41598-025-14425-x