Lyophilized Extracellular Vesicles from Adipose-Derived Stem Cells Increase Muscle Reperfusion but Degrade Muscle Structural Proteins in a Mouse Model of Hindlimb Ischemia-Reperfusion Injury

Ischemia-reperfusion (I/R) injury is a complication impacting multiple organs and tissues in clinical conditions ranging from peripheral arterial disease to musculoskeletal trauma and myocardial infarction. Stem cell-derived extracellular vesicles (EVs) may represent one therapeutic resource for pre...

Full description

Bibliographic Details

Published in:	Cells
Main Authors:	Bharati Mendhe, Mohammad B. Khan, Damon Dunwody, Khairat Bahgat Youssef El Baradie, Kathryn Smith, Wenbo Zhi, Ashok Sharma, Tae Jin Lee, Mark W. Hamrick
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	annexin a1 Hsp90 mitochondrial permeability exosomes dystrophin
Online Access:	https://www.mdpi.com/2073-4409/12/4/557