What evidence is there for the homology of protein-protein interactions?
The notion that sequence homology implies functional similarity underlies much of computational biology. In the case of protein-protein interactions, an interaction can be inferred between two proteins on the basis that sequence-similar proteins have been observed to interact. The use of transferred...
| Published in: | PLoS Computational Biology |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23028270/?tool=EBI |