C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity

C-type natriuretic peptide (CNP) is highly expressed in the central nervous system (CNS) and key to neuronal development; however, a broader role for CNP in the CNS remains unclear. To address this deficit, we investigated behavioral, sensory and motor abnormalities and blood-brain barrier (BBB) int...

Full description

Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Cristina Perez-Ternero, Patrick N. Pallier, Jordi L. Tremoleda, Alessio Delogu, Cathy Fernandes, Adina T. Michael-Titus, Adrian J. Hobbs
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Subjects:	C-type natriuretic peptide natriuretic peptide receptor C blood brain barrier ZO-1 seizure hyperactivity
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.991112/full