Phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART) SWOG S1609: the desmoid tumors

Background Dual inhibition using anti-programmed death-1 (PD-1) and anti-cytotoxic T-lymphocyte antigen-4 (CTLA-4) checkpoint inhibitors has proven effective in many cancers. However, its efficacy in rare solid cancers remains unclear. Desmoid tumors are ultrarare soft-tissue tumors, traditionally t...

Full description

Bibliographic Details
Published in:Journal for ImmunoTherapy of Cancer
Main Authors: Howard Streicher, Elad Sharon, Razelle Kurzrock, Young Kwang Chae, Megan Othus, Sandip Patel, Christine McLeod, Charles Blanke, Benjamin Powers, Chung-Tsen Hsueh, Helen X Chen, Hye Sung Kim, Liam Il-Young Chung, Christopher W Ryan, Rangaswamy Govindarajan, Silvana Bucur
Format: Article
Language:English
Published: BMJ Publishing Group 2024-09-01
Online Access:https://jitc.bmj.com/content/12/9/e009128.full