A Novel DSPP Mutation in Dentinogenesis Imperfecta Shields Type II: Clinical, Genetic and Stem Cell Perspectives

Introduction and aims: To identify the genetic cause of dentinogenesis imperfecta type II (DGI-II) in a family, analyse tooth microstructure and evaluate functional defects in patient-derived stem cells (SHED) to explore genotype-phenotype links. Methods: A 13-member family with DGI-II underwent cli...

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发表在:	International Dental Journal
Main Authors:	Qianhua Gao, Zhongren Deng, Ling Yang, Kehong Liu, JiYun Yang, Qin Du
格式:	文件
语言:	英语
出版:	Elsevier 2025-10-01
主题:	Dentinogenesis imperfecta Dentin sialophosphoprotein Stem cells from human exfoliated deciduous teeth Shields type-II
在线阅读:	http://www.sciencedirect.com/science/article/pii/S0020653925002242