The Time-Dependent Role of Bisphosphonates on Atherosclerotic Plaque Calcification

Atherosclerotic plaque calcification directly contributes to the leading cause of morbidity and mortality by affecting plaque vulnerability and rupture risk. Small microcalcifications can increase plaque stress and promote rupture, whereas large calcifications can stabilize plaques. Drugs that targe...

Full description

Bibliographic Details

Published in:	Journal of Cardiovascular Development and Disease
Main Authors:	Amirala Bakhshian Nik, Hooi Hooi Ng, Manuel Garcia Russo, Francesco Iacoviello, Paul R. Shearing, Sergio Bertazzo, Joshua D. Hutcheson
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Subjects:	atherosclerotic plaque calcification calcification paradox bisphosphonates
Online Access:	https://www.mdpi.com/2308-3425/9/6/168