Bioactive Flavonoids Icaritin and Icariin Protect against Cerebral Ischemia–Reperfusion-Associated Apoptosis and Extracellular Matrix Accumulation in an Ischemic Stroke Mouse Model

Stroke, which is the second leading cause of mortality in the world, is urgently needed to explore the medical strategies for ischemic stroke treatment. Both icariin (ICA) and icaritin (ICT) are the major active flavonoids extracted from <i>Herba epimedii</i> that have been regarded as t...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Cheng-Tien Wu, Man-Chih Chen, Shing-Hwa Liu, Ting-Hua Yang, Lin-Hwa Long, Siao-Syun Guan, Chang-Mu Chen
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Subjects:	extracellular matrix icariin icaritin ischemic stroke middle cerebral artery occlusion
Online Access:	https://www.mdpi.com/2227-9059/9/11/1719